I was hesitant to order this puzzle because I am more a fan of artwork that embodies interesting scenery or a unique picture. This one looked like a mish-mash of psychedelic designs. Because of the many positive reviews, I took a chance and ordered. When I spilled the puzzle pieces out of the box I wondered, where are all these bright vibrant colors that many reviewers spoke of? The graphic on the website displayed the neon colors magnificently. This puzzle appeared dark and rather dim to me. The cut of the pieces was phenomenal. I would expect nothing less from Tara Flannery. As I built the puzzle and joined sections together, it was as if a light switch had been flicked to the"on" position. The vibrant colors lit up and emerged with a fantastic glow! This is a win, I said to myself. The puzzle was also challenging. Another win. Although it was titled "Stem Cell", I got a different vibe. It reminded me of some genius electrical experiment of the great Nikola Tesla. This puzzle holds great rebuild value. It is a keeper. I highly recommend this one!!!